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Triethylene Glycol Ethyl Ether: Commentary on a Modern Chemical Workhorse

Historical Development

Before we had sleek solvents for the electronics and coatings industries, chemists leaned on simple glycols—humble but powerful tools. Triethylene glycol ethyl ether (TEGEE) didn’t come out of nowhere. Its background goes back to the 20th-century boom in organic synthesis, when manufacturers grew hungry for solvents with finer-tuned boiling points and less aggressive reactivity, especially as paints, inks, and resins gained more complex recipes. After World War II, Western and Eastern chemical plants cranked out glycols and ethers for a rebuilding world hungry for cars, cleaner cities, and new infrastructure. TEGEE showed up as a step in between volatile small ethers like ethylene glycol ethyl ether and slower-evaporating siblings like tetraethylene glycol ethers. The stepwise chain elongation and etherification methods that created TEGEE also helped drive new industrial processes for pharmaceuticals and agricultural products, connecting it to broader progress in organic chemistry. Today, its presence in safety data sheets or paint recipes carries the legacy of more than half a century of chemical exploration.

Product Overview

This ether dresses simply. You’ll find it on a supply list as a colorless, clear liquid with a mild, faintly sweet scent, not much different from many other glycol ethers at first glance. Several brands list it as an industrial solvent or intermediate, but suppliers typically highlight its nice mix of solubility and evaporation rate. Chemists and formulators seem to appreciate how it dissolves tough resins, dyes, and some fats, bridging gaps between water-soluble and oil-soluble ingredients. The molecule’s ethyl group makes it less volatile than basic glycol ethers, but still far gentler in scent and behavior than heavier long-chain compounds. From paints and cleaners to textile processing, the sense is always the same: TEGEE acts as the quiet backbone of tweaks and boosts to performance, rarely stealing the show.

Physical & Chemical Properties

On paper, TEGEE looks like a strong middleweight. With a molecular formula of C8H18O4 and a molar mass sitting at 178.23 g/mol, it melts around -60°C and boils near 257°C, so it stays liquid under most practical conditions. The density sits close to 1.01 g/cm³ at room temperature, placing it right in water’s territory but with its own chemical personality. The viscosity is moderate—not too runny and not so thick it gums up pumping systems. It mixes well with water, lower alcohols, and many hydrocarbons, which means you don’t face headaches trying to dissolve tricky resins or polymers. Not every glycol ether pulls this off with such ease, and that’s why it gets nods from formulators. Its vapor pressure stays low, so workplace concentrations don’t spike too fast in ventilated labs or plants, but the faint odor warns workers when the stuff lingers.

Technical Specifications & Labeling

Factories demand clear numbers. TEGEE typically arrives at purities of 98% or better, since impurities risk fouling up reactions or ruining delicate coatings. Labels list boiling and melting points, flash point (often just above 110°C for this compound), and essential handling codes. Safety data sheets always emphasize its moderate flammability—you won’t ignite a workspace with a stray spark, but caution matters. Barrel and drum labels carry GHS pictograms and plain hazard warnings about eye and skin irritation, nudging users towards gloves, goggles, and good ventilation. Some suppliers will provide batch-specific certificates of analysis, confirming water content below 0.1%, color clarity, and absence of stabilizers for certain sensitive syntheses. Out in the loading dock, hazmat teams want to see UN number 3082—a nod to its environmental persistence and aquatic toxicity—and clear transport codes.

Preparation Method

In the plant, nobody waves a magic wand—TEGEE preparation sticks to basic chemistry, just at industrial scale. The process usually starts with triethylene glycol, itself made by ethoxylation followed by distillation. Chemists use an ethylating agent like ethyl chloride or diethyl sulfate reacting with triethylene glycol in the presence of an alkaline catalyst. Coat everything with nitrogen or another inert gas: these reactions produce toxic by-products if air slips in. The resulting mixture demands a tough, precise fractional distillation to separate the ether from close-boiling kin. This means tight temperature controls, acid-washed glassware, and a nose for impurities. Some facilities use continuous flow systems for efficiency, relying on computer-linked process controls to avoid overheating or side reactions. Although the steps sound simple, the cost of raw materials and the risk of hazardous waste make TEGEE synthesis a job for well-equipped, well-trained staff.

Chemical Reactions & Modifications

Once in-hand, TEGEE works as a versatile building block. Its main appeal comes from the stable ether linkages, which shrug off many acids and bases, so TEGEE doesn’t decompose or react too easily during storage or use. Under strong enough conditions—with high heat or specialized catalysts—it can undergo ether cleavage, breaking down to smaller glycols or alcohols. Chemists might oxidize the terminal alcohol to create carboxylic acids or use it in Williamson ether syntheses, linking other groups for specialty molecules. Many of these variations stay tucked away in R&D labs, but a few commercial applications have emerged in surfactants and as modified solvents for tailor-made polymer recipes. Its resilience under many conditions gives a kind of chemical reliability that makes it useful in both routine and experimental work.

Synonyms & Product Names

Walk through the storeroom and you’ll spot TEGEE hiding behind a stack of synonyms. Suppliers call it by IUPAC’s “2-(2-(2-ethoxyethoxy)ethoxy)ethanol”; others stick with “Triethylene glycol monoethyl ether” or “TEGEE” on spec sheets. European datasheets sometimes mention “Ethoxytriglycol.” Other catalogues list numbers like CAS 112-50-5 or EINECS 203-978-9, which link back to stricter regulatory entries. Some niche suppliers use old trade names, but most users stick to TEGEE out of habit and ease. Any chemist who spends a few hours searching safety data sheets or patent filings quickly learns why clearing up these aliases matters: confusion over product name or number can send the wrong drum to the wrong production line, or worse, invite regulatory fines.

Safety & Operational Standards

Direct hands-on experience shows why safety matters with glycol ethers. I remember a colleague who dipped ungloved hands into a test batch, only to develop a rash after repeated exposure. Even without acute toxicity, TEGEE can cause lasting problems from skin absorption or inhalation in confined spaces. Regulations set exposure limits—usually around 10 ppm for an eight-hour shift—and plants rely on real-time sensors to keep vapors down. Workers wear gloves and splash goggles, and exhaust fans hum near mixing and bottling stations. Drum spills demand fast action: absorbents, contained disposal, prompt area cleaning. In an emergency, first responders ask for information sheets that describe chemical and fire hazards, and local wastewater rules block uncontrolled disposal. Firms that ignore these steps risk injury, fines, or environmental damage that quickly bites into profit, reputation, and morale. Awareness and discipline matter more than a long checklist.

Application Area

Most TEGEE heads for coatings, inks, and cleaners. Its slow evaporation rate lets paint layers dry smoothly, avoiding the jagged lines and bubbles that fast-drying solvents cause. Ink factories blend it into jet printer formulations, where it keeps pigment particles in motion without clogging nozzles. Textile plants use it to help dyes penetrate synthetic fibers, while specialty cleaners rely on its ability to dissolve grease without punching holes in sensitive plastics or finishes. Occasionally a battery manufacturer or pharmaceutical lab will pull TEGEE off the shelf for pilot batches, testing how it interacts with new compounds. No matter the end use, the pattern holds: flexibility, friendly handling, and steady supply win the day, but only if companies buy from reputable dealers and follow the safety playbook.

Research & Development

Researchers keep chipping away at TEGEE’s potential. Coating chemists still hunt for better dispersants and anti-cracking additives; TEGEE’s unique structure offers a foundation for these new molecules. Green chemistry teams look into bio-based routes for producing TEGEE, aiming to squeeze fossil fuels out of the supply chain by using plant-based feedstocks or incorporating recycled glycols. Lab teams also seek safer glycol ether blends, testing TEGEE in conjunction with newer, less toxic ethers or vegetable-oil derived solvents for lower-impact products. Custom surfactant development and molecular imprinting protocols show up in recent patents, hinting at new directions where TEGEE’s backbone gives a balance between stability and functionality. Real-world progress moves slowly, tangled in price pressures or regulatory shifts, but the drumbeat of small innovations continues.

Toxicity Research

Decades of study have mapped out most of TEGEE’s risks. Acute toxicity lands in the mild-to-moderate range; swallowing even moderate amounts makes you queasy, dizzy, and possibly gives liver trouble, but outright fatalities are rare outside large spills or accidents. Animal testing shows effects on kidney and reproductive systems at high, repeated doses. Occupational health studies watch for chronic effects, especially in warehouse packers or cleaning staff. Regulatory authorities flag both the chemical’s potential for skin absorption and its slow breakdown in water, warning users to limit groundwater contamination and to avoid letting the solvent build up inside living spaces. Long-term epidemiological data still lacks clear links to cancer, but the sense is clear: gloves, masks, and good engineering controls stay necessary, especially in tight or poorly-vetted working conditions.

Future Prospects

Looking ahead, TEGEE’s fate hinges on a larger question: can legacy chemical tools offer cleaner, more efficient solutions? As tighter regulations squeeze out problematic glycol ethers, TEGEE’s relatively low volatility, mild odor, and steady market demand give it a fighting chance—at least in coatings, electronics, and specialty surfactants—provided ongoing toxicity and environmental concerns get managed responsibly. Companies exploring sustainable chemistry might find new life for TEGEE by tying its manufacturing to greener processes or recycling, rather than new fossil resources. Safety tech will keep pushing forward, with improved handling gear and better monitoring of workplace exposure. Innovation always balances risk and reward, and chemicals like TEGEE—reliable, familiar, but not without baggage—force both industry insiders and regulators to keep asking hard questions about trade-offs, responsibility, and the kind of progress worth chasing.



What are the main applications of Triethylene Glycol Ethyl Ether?

What Does Triethylene Glycol Ethyl Ether Do?

Triethylene Glycol Ethyl Ether, often shortened to TEGEE, doesn’t show up in everyday conversation, but it does show up in a variety of products and industrial settings. Its chemical formula gives it plenty of flexibility, making it more than a one-trick pony. In the real world, the fuss about TEGEE comes from the way it works as a solvent, helping other chemicals do their job more effectively. Most folks outside of a lab don’t think about solvents beyond the paint aisle, but these chemicals play a big role well beyond making pigment spread easily or clean up smudges.

Solvents Make Things Go Round

TEGEE’s main gig is as a solvent in coatings and inks. Without a good solvent, paint sits thick, sticky, and tough to manage. I’ve rolled enough rooms and used enough spray finishes to know that the wrong base makes for a patchy, unreliable mess. TEGEE helps paint remain smooth, giving it the right flow so surfaces don’t look like they got hit with a layer of frosting. Printing inks also rely on this chemical, especially when manufacturers want bright patterns to stick to packaging or fabrics without streaks or smears.

Helping Cleaners Work Harder

Industrial cleaning is another territory where TEGEE has found a home. Factories and offices can’t get by with warm water alone. Floors and machinery gather all kinds of stubborn grime, oils, and resins. Standard soap doesn’t cut it. TEGEE boosts the power of cleaning products, letting them cut through layers of tough residue. Anyone who’s tried to clean a greasy auto part or sticky kitchen vent knows standard approaches fall short. Solvents like this get the job done, improving safety and efficiency for workers who’d otherwise spend all day scrubbing.

The Hidden Helper in Electronics

Electronics demand excellent precision, from the surface of circuit boards to the delicate innards of a touchscreen. Dust, oils, and leftover soldering compounds spell trouble, making everything from your smartphone to factory sensors glitchy. TEGEE’s chemical stability allows it to act as a gentle yet potent cleaner for these sensitive surfaces. Over the years, experts in electronics have turned to TEGEE because it doesn’t eat away at tiny wires or leave behind residues that could interfere with delicate circuitry.

Main Player in Chemical Synthesis

Chemists working on pharmaceuticals, adhesives, and even fragrances need trusted chemicals to kickstart reactions or carry ingredients. TEGEE works well for this kind of preparation. In labs, accurate and safe delivery of ingredients has become more important as stricter standards pop up. By choosing ingredients like TEGEE, companies reduce mistakes and improve batch quality—both things I’ve seen make or break a business in manufacturing.

Safer Options Without Sacrifice

Chemical safety keeps cropping up in conversation, especially among neighbors who worry about what companies send into the air or down the drain. Thankfully, TEGEE sits among solvents that generally score lower for toxicity than the harshest alternatives. It still carries risks if handled poorly—nothing good comes from cutting corners—so proper training and equipment remain standard in factories and labs. A safer alternative doesn’t mean a free-for-all, but it helps shift the needle toward better conditions for everybody on the production line and downwind from the plant.

Where Do We Go From Here?

Industries could take another look at how many solvents they use and keep searching for greener replacements. Environmental pressure isn’t letting up, and communities expect improvements. If better alternatives become available, manufacturers would benefit by testing and phasing them in. Lining up with health and safety rules not only reduces fines; it also brings in quality-minded clients who want peace of mind. For now, TEGEE stays valuable, not just because it works, but because it keeps companies moving forward on safety without disrupting their core business.

Is Triethylene Glycol Ethyl Ether hazardous to human health?

Understanding the Substance

Triethylene glycol ethyl ether pops up in all sorts of industrial settings, from cleaners to paints and even a few personal care products. With a long chemical name like that, it’s easy to lose sight of what it actually does. Most folks never see it in pure form, but that doesn’t mean it quietly passes through our lives. I’ve handled chemicals during a stint at an auto body shop, and vigilance stuck with me ever since. Some solvents sting the eyes and throat. Others just leave you guessing until the safety data sheet drops a warning in your lap.

Potential Health Risks

This ether isn’t something you’d pour down the drain or forget on a shelf. Breathing its fumes could irritate the nose and cough up trouble in the lungs. I remember the splutter after the wrong solvents got mixed during a late-night project—one real whiff cleared the shop quick. Prolonged or repeated skin contact may cause redness or dry patches, especially if folks skip gloves. The weird thing with chemicals like this: low-level contact rarely sparks an instant reaction, but over weeks or months, little side effects—headaches, fatigue—creep up for people who work around it all day.

Most published studies focus on acute exposure. Brief run-ins don’t stack up to chronic risks, and that’s where research still leaves questions hanging. The jury’s out on whether this ether causes long-term nerve or kidney effects. No one has flagged it as a major carcinogen, which helps, but a lack of evidence doesn’t equal an all-clear. Given the way these molecules move through the air, especially in poorly ventilated places, nobody dealing with them should get comfortable and toss precautions aside.

Level of Danger and Regulations

The industry calls it “moderately hazardous”—not bleach, but far from harmless. OSHA sets exposure limits for common solvents, though gaps exist for lesser-known ones. European regulators slot this ether in with substances needing careful handling, especially in cosmetics or cleaning products. If you make a habit of checking product labels (as I do after cleaning mishaps from the early years), you’ll catch these names nested among ingredients. Manufacturers add them for specific reasons—solubility, fast drying, spreading ease—but often don’t make them prominent.

Why It Matters

No single product flips the switch on a health crisis. Instead, the slow build from repeated, unchecked exposure creates trouble down the line. I’ve watched coworkers skip gloves or masks to save time, dismissing warnings as worry for someone else. The symptoms start subtle—dry skin, an irritated throat. If caution sounds dull, it’s often because harm stays hidden until the line gets crossed.

Past mistakes teach plenty. Cheap fixes and shortcuts invite bigger problems. Strong workplace rules make a difference: improved ventilation, regular safety training, and honest communication about what's in the chemicals people use can spare a lot of grief. For everyday consumers, curiosity about what’s in a bottle goes a long way. If the label draws a blank, a quick online search or a check with the supplier can spot a hazard before it turns into a headache—literally and figuratively.

Better Habits and Smarter Choices

I grew up around folks who took pride in getting the job done fast. Later, I saw that small investments—good gloves, working fans, real training—kept everyone healthier. Nobody should have to wonder if their job or home routine puts their health on the line for lack of knowledge. Armed with a few facts, anyone can ask sharper questions, and push for fixes before problems start. Triethylene glycol ethyl ether doesn’t need to star in a health scare for people to treat it with care.

What is the chemical formula and structure of Triethylene Glycol Ethyl Ether?

Looking Beyond Fancy Names: What’s in Triethylene Glycol Ethyl Ether?

The chemical world throws around some heavy-duty names, and Triethylene Glycol Ethyl Ether packs quite a few syllables for such a useful solvent. If we break it down, its formula is C8H18O4, which tells anyone familiar with basic chemistry that we’re talking about a molecule with eight carbon atoms, eighteen hydrogens, and four oxygens. Not exactly something you spot hanging out in your backyard, but you might find it on a list in a plant making paints, cleaners, or specialty coatings.

The structure of Triethylene Glycol Ethyl Ether helps explain why it works so well in these contexts. This compound pieces together three ethylene glycol units, bridged by oxygen atoms, and caps off one end with an ethyl group (that’s the “ethyl ether” bit). If someone wanted to sketch this thing out, they’d start with an ethyl group (–C2H5), connect that to a chain of three –CH2CH2O– units, and end up with a terminal hydroxyl (–OH). Chemists write the structure as CH3CH2O(CH2CH2O)3H. That repeat unit in the middle can take on different lengths in other glycol ethers, but three is the magic number for this one.

Structure Fuels Functionality

In everyday talk, structure decides what a chemical can do. Those repeating ethylene oxide sections act a bit like Velcro for both water and oil, letting this compound dissolve into some pretty tough mixtures. That’s why manufacturers use it for blending resins, cleaning up tricky stains, or improving the flow of inks. Its backbone makes it less toxic compared to many other solvents, but it stays effective at helping materials slip, slide, and disperse.

From my own tinkering with solvents in art and lab work, it’s the balance between water-loving and oil-loving parts in chemicals like Triethylene Glycol Ethyl Ether that makes life so much easier. Imagine trying to get oil-based paint out of fabric with nothing but water—doesn’t really cut it. A bottle of this stuff, used right, can dissolve messes without ruining the material. That’s not magic, just clever chemistry thanks to those glycol ether chains and flexible molecular design.

Environmental and Health Considerations

Of course, every solvent has a story outside the lab. Triethylene Glycol Ethyl Ether brings a lower toxicity profile than plenty of other ethers, but it’s still a synthetic chemical. Spills or improper disposal could spell trouble for waterways or groundwater. Regulations exist for good reason, keeping anyone handling this compound honest about its risks. Splash protection, good ventilation, and responsible waste management matter as much as the formula itself.

Some folks in the chemical industry have started working with bio-based glycol ethers, cutting ties with petroleum and reducing lingering health concerns. There’s a push to tweak molecular structures for improved biodegradability, and tighter workplace exposure limits reflect lessons learned from real-world accidents. In my experience, small changes—like choosing a slightly bulkier glycol ether that breaks down faster in sunlight—can help keep a shop or lab safer without slowing down production one bit.

Toward Smarter Use

Getting familiar with the ins and outs of Triethylene Glycol Ethyl Ether helps shoppers, scientists, and workers make better decisions. Respecting the molecular structure gives us power to mix thoroughly, clean safely, and protect our environment. The more we understand these chemicals—beyond their stretched-out names—the easier it gets to pick the right tool, handle it with care, and push toward greener solutions altogether.

How should Triethylene Glycol Ethyl Ether be stored and handled?

What I’ve Seen on the Shop Floor

There’s no fancy name for it—Triethylene Glycol Ethyl Ether comes in as a clear, slightly viscous liquid. The guys at the plant used to give me a sideways look every time a new drum rolled in. Some laughed it off, others looked worried. I remember the first spill I saw: someone cracked open the seal and, boom, a cloud of vapor wafted up. No one thought too much at first. Over time, I learned that a substance like this doesn’t forgive sloppiness.

Straight Talk About Storage

A chemical with a high flash point like this one tries to lull people into thinking it isn’t so bad. That’s a mistake. It’s often left in steel drums and poly containers. Trouble starts if those drums sit in the sun. Overheating means pressure builds, seals bulge, and one day, someone gets unlucky. I’ve watched managers cut corners—stacking drums in aisles, storing them near welding gear or water lines. Not many people talk about how water can seep into a drum and kick off some unpredictable chemistry inside. I’ve seen white residue form at the bottom of containers, and the lead operator had to stop the line and figure out what was happening. Stored right, in a cool, well-ventilated space, sealed against moisture and sunlight, the stuff stays docile.

Handling Isn’t About Guesswork

Back in my early days, I watched a co-worker fill a pump without gloves. By lunchtime, redness bloomed on his skin. Some people think “mild irritant” means harmless. After that incident, gloves and goggles became as routine as safety boots. It shouldn’t be optional. Vapors don’t always announce themselves, either. In small rooms or freight containers, the invisible risk to lungs grows fast. Even folks who avoid direct contact can forget the vapor. In the past, I’ve used fans to ventilate a busy decant area. Sometimes, people prop open doors for air, but that invites dust or moisture, which makes things worse.

Lessons from Experience—and Smart Fixes

Facilities that treat chemicals like gadgets—setting and forgetting—face problems. The best-run places use simple checklists: lids on tight, labels clear, spill kits topped up, fire extinguishers handy. Not because rules say so, but because trying to remember it all leaves room for error. Once I saw a plant swap out old containers that had hairline cracks. The manager said, “Spend the money now or pay for the cleanup later.” He was right. If management invests in chemical-proof bunds and regular inspections, accidents drop.

Training new people goes beyond reading the MSDS out loud. It helps to walk the floor, point out where leaks start, remind them not to eat or drink nearby, and show what to do if things go wrong. I started out nervous around solvents like these, but over time, you appreciate how small routines—checking the thermometer, testing vent fans, keeping workspaces tidy—prevent big problems. Local exhaust ventilation beats window fans. Reliable gloves and aprons work better than hoping for the best.

Why This Stuff Deserves Respect

Triethylene Glycol Ethyl Ether comes with risks, and shrugging off best practices invites pain, property damage, or worse. Especially with young staff, it pays to make safety visible, normal, uncompromising. I’ve walked away from a shift thinking all went well, only to hear about a close call in the next department. With chemicals like these, small mistakes build up. Storing, labeling, and handling right—every day, every shift—keeps everyone safe. It’s not glamorous, but it works.

What are the typical purity grades and packaging options available for Triethylene Glycol Ethyl Ether?

Understanding Purity Grades

Triethylene Glycol Ethyl Ether pops up in places ranging from coatings to cleaners. Each setting expects a slightly different spec, but most commercial suppliers focus on a few common purity levels. The most widely used is the industrial grade, carrying a typical purity between 97% and 99%. Manufacturers push for higher figures when this solvent enters the lab or pharma space—these high-purity grades often top 99%. This jump isn’t about bragging rights; trace impurities make a big difference if you’re running chemical reactions or mixing custom formulations for sensitive jobs.

My experience tells me that paying extra for “high purity” almost always reflects more careful distillation and equipment cleaning behind the scenes. It’s not something you spot with the naked eye, but lab-grade Triethylene Glycol Ethyl Ether usually comes backed by a certificate, laying out just what impurities are present—down to fractions of a percent. For folks mixing paints or inks, standard grades work fine, since tiny leftover byproducts don’t throw off performance. People planning to blend ingredients for electronics, pharmaceuticals, or analytical testing need those numbers squeaky clean. Even a trace of residual aldehydes or water makes a difference, since the compound can pick up extra moisture from the air during storage.

Packing, Storing, and Shipping

Now, storage and transportation influence cost and safety just as much as purity. Most industrial buyers look for 200-liter steel or plastic drums. These barrels seal airtight with gaskets that stand up to hydrocarbon solvents. Moving bigger volumes? Stainless steel totes or ISO tanks become common. I’ve dealt with suppliers filling up 1,000-liter intermediate bulk containers (IBCs) for plants running high-throughput applications—a single IBC saves money on bulk orders, although these take up a hefty chunk of warehouse floor.

Labs and research outfits run smaller scale. They opt for 1-liter or 5-liter glass or HDPE bottles. These handy containers resist solvent damage and make handling easier in the lab. Some high-purity batches travel in amber glass for blocking out light, paired with shrink-sealed lids and detailed batch tracking stickers. Working through different suppliers, I’ve noticed that the best ones never skimp on this last mile—they include tamper-evident caps and extra layer packaging for shipments in hot or unpredictable weather. Better peace of mind for storage, fewer surprises from spilled drums or leaky bottles during shipping.

The Value of Packaging in Real-World Use

Costs for safe storage stack up quickly, especially if drums wait weeks or months before use. I’ve seen shops cut corners, storing half-used barrels without proper gaskets, and ending up with contaminated material. Moisture and air seep in, turning good product into waste. Specialty applications—think chromatography or electronics—justify spending more on both purity and packaging, since one batch slip-up could throw off much bigger projects.

Distributors sometimes offer smaller sample kits, maybe 100 or 250 milliliters, for users running pilot tests before scaling up. This helps new users figure out if Triethylene Glycol Ethyl Ether solves their problem, without a huge upfront spend or safety risks from full drums.

Every part of the supply chain, from purity levels to final drum or bottle, tells you where the product’s headed and how careful you’ll need to be during use. In practice, the real challenge lies not just in buying the right chemical, but in keeping it clean, dry, and secure until it reaches its final destination.

Triethylene Glycol Ethyl Ether
Triethylene Glycol Ethyl Ether
Names
Preferred IUPAC name 2-(2-(2-ethoxyethoxy)ethoxy)ethanol
Other names Ethoxytriethylene glycol
3,6,9-Trioxa-1-undecanol
Triethylene glycol monoethyl ether
TEGEE
Ethyl triethylene glycol
Pronunciation /traɪˌɛθaɪliːn ɡlaɪˌkɒl ˈiːθəl ˈiːθə/
Identifiers
CAS Number 112-50-5
Beilstein Reference 803094
ChEBI CHEBI:51331
ChEMBL CHEMBL1697827
ChemSpider 21106511
DrugBank DB14006
ECHA InfoCard 03e29350-2435-467c-b032-c8d2d088ca23
EC Number 203-977-3
Gmelin Reference 116676
KEGG C18712
MeSH D014278
PubChem CID 8217
RTECS number KO4825000
UNII RU45X2JN7Z
UN number UN1993
Properties
Chemical formula C8H18O4
Molar mass 178.23 g/mol
Appearance Colorless transparent liquid
Odor Odorless
Density 0.988 g/cm³
Solubility in water Miscible
log P 0.44
Vapor pressure 0.013 mmHg (20 °C)
Acidity (pKa) ~15.1
Magnetic susceptibility (χ) -67.0e-6 cm^3/mol
Refractive index (nD) 1.432
Viscosity 7.2 mPa·s at 25°C
Dipole moment 2.96 D
Thermochemistry
Std molar entropy (S⦵298) 395.7 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -738.65 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -4444 kJ/mol
Pharmacology
ATC code D07AX
Hazards
GHS labelling GHS02, GHS07
Pictograms GHS07,GHS08
Signal word Warning
Hazard statements H319: Causes serious eye irritation.
Precautionary statements Precautionary statements: "P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P305+P351+P338, P370+P378
NFPA 704 (fire diamond) 1-2-0
Flash point 185°C
Autoignition temperature 204°C
Explosive limits Explosive limits: 1.1% - 10.6%
Lethal dose or concentration LD50 Oral Rat 6,900 mg/kg
LD50 (median dose) LD50 (median dose): 3,700 mg/kg (oral, rat)
NIOSH WX8600000
PEL (Permissible) Not established
REL (Recommended) 25 ppm
Related compounds
Related compounds Ethylene Glycol
Diethylene Glycol
Triethylene Glycol
Tetraethylene Glycol
Ethylene Glycol Monoethyl Ether
Diethylene Glycol Monoethyl Ether
Polyethylene Glycol
Ethylene Oxide