Product Name: Triethylene Glycol Dimethyl Ether
Synonyms: TEGDME, Triglyme, 2,5,8,11-Tetraoxadodecane
CAS Number: 112-49-2
Recommended Uses: Solvent, battery electrolyte, laboratory reagent
Supplier Details: Company name, emergency phone number, address, email (see appropriate vendor or distributor)
Physical State: Clear, colorless liquid
GHS Classification: Flammable liquid (Category 4), Reproductive toxicity (Category 2), Eye irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Combustible liquid. Suspected of damaging fertility or the unborn child. Causes serious eye irritation.
Pictograms: Exclamation mark, health hazard
Precautionary Statements: Avoid release to environment, wear protective gloves/eye protection, keep away from heat or sparks, do not breathe vapor or mist, wash hands thoroughly after handling
Chemical Name: Triethylene Glycol Dimethyl Ether
Concentration: >98%
CAS: 112-49-2
Impurities: Minor glyme derivatives possible (<2%)
Inhalation: Move to fresh air. If symptoms develop, seek medical attention. Respiratory support may be needed in some cases.
Skin Contact: Remove contaminated clothing. Wash thoroughly with soap and water. Irritation may occur, so medical advice is a good move.
Eye Contact: Rinse with plenty of water for at least 15 minutes, holding eyelids apart. Contacts need to come out. Medical review is recommended.
Ingestion: Rinse mouth with water. Keep patient calm. Seek immediate medical attention—do not induce vomiting unless told so by medical staff.
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, or CO2. Water spray can help cool containers but may not extinguish.
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, possible formaldehyde
Special Protective Equipment: Firefighters wear self-contained breathing apparatus, full protective clothing
Special Hazards: Vapors may form explosive mixtures with air. Closed containers can build pressure under heat.
Personal Precautions: Avoid breathing vapors. Ventilate area well. Keep away sources of ignition.
Spill Cleanup: Absorb with inert material like vermiculite or sand. Transfer to closed waste container. Clean spill area with water.
Environmental Precautions: Prevent from entering soil, ditches, sewers, or waterways. Notify authorities if a large spill threatens the environment.
Protective Equipment: Wear gloves, goggles, chemical-resistant clothing.
Handling: Work only with proper ventilation. Use non-sparking tools. Practice good industrial hygiene—wash hands after use, avoid eating, drinking, or smoking.
Storage Conditions: Store in cool, dry area, away from direct sunlight and sources of heat. Keep container tightly closed. Keep away from strong oxidizers, acids, and ignition sources.
Incompatible Materials: Avoid contacting strong oxidizing agents, acids, and bases.
Exposure Limits: No established OSHA, ACGIH, or NIOSH limits for this compound; use engineering controls to minimize exposure.
Engineering Controls: Use mechanical ventilation, fume hoods, or local exhaust in enclosed areas.
Personal Protection: Chemical-resistant gloves (nitrile or neoprene), safety goggles, protective clothing. In heavy vapor areas, use approved respirators.
Hygiene: Remove contaminated clothing and wash before reuse. Wash hands before breaks and after handling chemicals.
Appearance: Clear, colorless liquid
Odor: Mild, ether-like
Odor Threshold: Not available
pH: Not available (neutral compound)
Melting Point/Freezing Point: -45°C
Boiling Point/Range: 216°C
Flash Point: 102°C (closed cup)
Evaporation Rate: Low
Explosive Limits: Lower: 0.9%, Upper: 15% (v/v)
Vapor Pressure: 0.03 mm Hg (20°C)
Vapor Density: 6.1 (air=1)
Relative Density: 0.96 g/cm3 (20°C)
Solubility: Miscible in water
Partition Coefficient (n-octanol/water): -0.54
Auto-Ignition Temperature: 221°C
Decomposition Temperature: Not established
Viscosity: 5.5 mPa·s (20°C)
Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Not highly reactive, but can form peroxides upon prolonged air exposure
Hazardous Reactions: Can react with oxidizers, acids, bases; avoid strong agents, as this can trigger runaway reactions
Conditions to Avoid: Heat, flames, sparks, direct sunlight, air exposure
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, formaldehyde, other aldehydes
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Low to moderate; Oral LD50 (rat) 2,100 mg/kg
Skin/Critical Organ Effects: May cause mild irritation, dryness
Eye Contact: May irritate, cause redness, watering
Respiratory Effects: At high levels, may lead to dizziness, headache, or nausea
Chronic Toxicity: Potential reproductive toxin—studies suggest possible impacts on fertility and fetal development
Sensitization: No confirmed data
Mutagenicity/Carcinogenicity: No clear evidence in standard animal assays
Environmental Impact: Not readily biodegradable; persists in the environment
Aquatic Toxicity: LC50 (fish, 96 hr) >10,000 mg/L—low to moderate risk for aquatic life
Bioaccumulation Potential: Low—partition coefficient suggests rapid breakdown, no significant buildup in organisms
Mobility: Readily soluble in water, may move easily through soil and water systems
Persistence: Degradation in environment is slow
Waste Treatment: Dispose in accordance with federal, state, and local regulations
Incineration: Preferred method for larger volumes; avoid release to air without emission controls
Contaminated Packaging: Rinse thoroughly before reuse, or dispose of as hazardous waste
Special Precautions: Do not pour down drain or into soil
UN Number: Not regulated (DOT/ADR/IMDG/ICAO)
Proper Shipping Name: Not classified as dangerous for transport
Packing Group: Not assigned
Hazard Class: Not assigned
Special Transport Precautions: Keep containers sealed upright, prevent leaks in transit, store away from oxidizers or acids during transport
TSCA Status: Listed
REACH Status: Registered
SARA Title III: Not specifically listed as reportable
California Proposition 65: Not listed
Other Local Regulatory Info: Consult local chemical safety regulations for specific requirements on use, storage, and reporting
