Product Name: Tetraethylene Glycol Dimethyl Ether
Synonyms: Tetraglyme, 2,5,8,11-Tetraoxadodecane, Dimethyl Tetraethylene Glycol
CAS Number: 143-24-8
Recommended Use: Laboratory solvent, electrolytes, chemical synthesis
Supplier: Local or international chemical manufacturers and laboratory suppliers
Emergency Contact: Refer to manufacturer or local emergency response number
Physical State: Colorless, oily liquid
Classification: Flammable liquid, eye irritant, may cause skin irritation
Hazard Statement: Vapors can form explosive mixtures with air, contact with skin or eyes may lead to irritation, inhalation may lead to dizziness or headaches, prolonged exposure can affect the central nervous system
Pictograms: Flame, exclamation mark
Precautionary Measures: Avoid inhalation, use protective gear, keep away from ignition sources
Chemical Name: Tetraethylene Glycol Dimethyl Ether
CAS Number: 143-24-8
Concentration: Approximately 100%
Impurities/Additives: Granted technical grade, trace amounts of related glycol ethers may be present depending on manufacturer
Inhalation: Remove person to fresh air, loosen clothing, seek medical advice if symptoms such as dizziness or coughing persist
Skin Contact: Wash immediately with soap and water, remove contaminated clothing, monitor for redness or irritation
Eye Contact: Rinse thoroughly with water for several minutes, remove contact lenses if easy, seek medical attention if discomfort remains
Ingestion: Rinse mouth, do not induce vomiting, consult a doctor or poison control center right away
Suitable Extinguishing Media: Use foam, dry chemical, carbon dioxide, do not use water jet directly on burning liquid
Special Hazards: Vapors can travel significant distance to ignition source, combustion produces toxic fumes including carbon monoxide and carbon dioxide
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Advice: Cool exposed containers with water spray to limit risk of explosion, evacuate area if needed
Personal Precautions: Put on chemical-resistant gloves, goggles, appropriate respirator, prevent ignition sources
Environmental Precautions: Prevent product from entering drains or waterways, report significant spill to local authorities
Cleanup Methods: Absorb with inert material such as sand or vermiculite, place in chemical waste container, ventilate area and wash spill site after cleanup
Safe Handling: Work outdoors or in well-ventilated place, ground and bond containers, avoid breathing vapor, avoid skin and eye contact
Storage Conditions: Keep container tightly sealed in a dry, cool, and well-ventilated area, store away from heat, sparks, open flames, and even mildly oxidizing agents
Incompatible Materials: Oxidizers, acids, and strong bases
Exposure Limits: No national occupational exposure limits have been set for this chemical in most regions
Engineering Controls: Use local exhaust or general dilution ventilation to minimize exposure
Personal Respiratory Protection: Use NIOSH-approved organic vapor respirator if vapor concentrations are high
Skin Protection: Nitrile or butyl rubber gloves, lab coat or chemical apron protects skin
Eye Protection: Chemical splash goggles
Hygienic Practices: Wash hands after handling, do not eat, drink or smoke near chemical
Appearance: Clear, colorless, oily liquid
Odor: Data sparse, slight ether-like smell
Odor Threshold: Not established
pH: Not applicable
Melting Point/Freezing Point: About -50°C
Boiling Point: About 275°C
Flash Point: Approximately 136°C (closed cup)
Evaporation Rate: Slow
Flammability: Combustible
Vapor Pressure: Low (0.02 mmHg at 25°C)
Vapor Density: Heavier than air
Solubility: Miscible in water and many organic solvents
Partition Coefficient (n-octanol/water): 0.56
Auto-ignition Temperature: About 245°C
Decomposition Temperature: Not well defined
Viscosity: Moderate, around 8 cP at 25°C
Chemical Stability: Stable under normal temperatures and pressures
Reactivity: Not highly reactive, reacts with potent oxidizers
Hazardous Reactions: Contact with acids, chlorinating agents, or oxidizers can produce dangerous products
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, other potentially toxic fumes
Conditions to Avoid: Heat, flames, sparks, static discharge, direct sunlight, incompatible chemicals
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Oral LD50 for rats (estimated) >5,000 mg/kg, inhalation LC50 data not robust, can cause drowsiness, headaches, irritation to lungs, eyes, and skin
Chronic Toxicity: Long-term exposure data limited, prolonged contact may affect central nervous system
Potential Effects: Repeated skin exposure may cause dermatitis, occasional reports of mild kidney effects in animal studies
Carcinogenicity: No direct evidence to indicate carcinogenicity according to IARC, ACGIH, NTP, or OSHA
Ecotoxicity: Low acute toxicity to aquatic organisms, fish LC50 (96h, est.) >100 mg/L
Degradability: Moderately biodegradable, slower than simpler glycol ethers
Bioaccumulative Potential: Partition coefficient suggests low potential for accumulation in aquatic life
Mobility in Soil: Highly soluble, moves readily through soil and groundwater
Other Adverse Effects: High concentrations may cause oxygen depletion in aquatic environments
Waste Disposal: Contact local hazardous waste service, incineration in authorized facility preferable, do not pour down drain
Container Handling: Triple rinse before recycling or disposal, dispose of rinsate as hazardous waste
Legal Requirements: Observe applicable local, regional, and national regulations
UN Number: Not regulated as hazardous for most forms of ground or sea transport
Proper Shipping Name: Tetraethylene Glycol Dimethyl Ether or Tetraglyme
Hazard Class: Usually not assigned a hazard class
Packing Group: None allocated for domestic shipment
Special Transport Precautions: Secure containers tightly, keep away from heat or ignition points in transit
TSCA: Listed
REACH: Registered and compliant under EU REACH
OSHA: Treated as a chemical hazard, general safety measures apply
WHMIS (Canada): Recognized under controlled products regulation
Other National Inventories: Typically found on Australian, Korean, Japanese, and Chinese chemical inventories
Restrictions: Not flagged for hormone interference or persistent organic pollutant risk, but workplace monitoring recommended if used at scale
