Adress Chemical
Knowledge


MSDS for Propylene Glycol Diacetate

Identification

Product Name: Propylene Glycol Diacetate
Chemical Formula: C7H12O4
Chemical Family: Glycol Esters
CAS Number: 623-84-7
Synonyms: PGDA, 1,2-Propanediol diacetate
Recommended Use: Solvent in coatings, inks, cleaners, adhesives
Manufacturer: [Manufacturer Name, Address, Contact Number]
Emergency Contact: [24-hour emergency number or CHEMTREC]

Hazard Identification

Classification: Irritant to eyes and skin, mild inhalation hazard
Label Elements: Warning symbol, “Causes serious eye irritation”, “May cause mild skin irritation”
Routes of Exposure: Skin contact, eye contact, inhalation, ingestion
Symptoms: Redness, itching, tearing, coughing, drowsiness with high exposure
Hazard Statements: Contact with eyes may produce irritation; skin exposure may lead to redness; prolonged inhalation of vapors can cause dizziness

Composition / Information on Ingredients

Chemical: Propylene Glycol Diacetate
CAS Number: 623-84-7
Concentration: >99%
Impurities: Water (<0.5%), acetic acid traces (<0.1%)
Stabilizers/Additives: None known

First Aid Measures

Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, seek medical attention if irritation persists
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, call a physician for persistent irritation
Inhalation: Move to fresh air, keep at rest, seek medical advice if symptoms like coughing or dizziness appear
Ingestion: Rinse mouth, do not induce vomiting, give water if conscious, get medical help immediately
Most Important Symptoms: Irritated or red eyes, dry skin, headache or nausea with heavy vapor exposure

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Media: Direct water jet might spread liquid fire
Special Hazards: Can release toxic fumes (acetic acid, carbon monoxide, carbon dioxide) during combustion
Specific Protective Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact
Special Procedures: Cool exposed containers with water, prevent spillage from entering drains or waterways

Accidental Release Measures

Personal Precautions: Use personal protective gear (gloves, goggles), avoid breathing vapors, ensure proper ventilation
Environmental Precautions: Prevent from entering sewers, drains, or waterways; contain spill on impermeable surface
Methods for Clean-Up: Contain with inert material (sand, earth), collect using non-sparking tools, place in designated waste containers, wash the area with water, ventilate
Other Notes: Large spills need emergency response and notification of local authorities

Handling and Storage

Handling Precautions: Avoid direct skin and eye contact, use only in spaces with adequate ventilation, do not ingest or inhale vapors, keep away from heat or ignition sources, ground all equipment properly
Storage Requirements: Store in tightly closed containers, use in cool, dry, well-ventilated area, keep separate from strong oxidizers or acids, avoid extreme temperatures, ensure containers are clearly labeled
Incompatible Materials: Strong acids, alkalis, oxidizing agents
Special Advice: Use explosion-proof equipment if vapor concentrations may build up

Exposure Controls and Personal Protection

Exposure Limits: No established workplace limits, minimize exposure as practice
Engineering Controls: Use local exhaust ventilation, closed systems where possible
Personal Protective Equipment: Nitrile or butyl rubber gloves, splash-proof goggles, lab coats or aprons
Respiratory Protection: Use NIOSH-approved organic vapor respirators for heavy vapor
Hygienic Practices: Wash hands after handling, remove contaminated clothes before breaks or meals

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Ester-like, faint fruity
Boiling Point: About 190°C (374°F)
Melting Point: About -57°C (-71°F)
Flash Point: 86°C (186°F) (closed cup)
Evaporation Rate: Slower than ether
Vapor Pressure: 0.16 mmHg at 20°C
Solubility: Miscible with most organic solvents, slightly soluble in water
Density: 1.07 g/cm³ at 20°C
pH: Not applicable
Partition Coefficient (log Kow): 0.37 ± 0.05
Viscosity: About 2.8 mPa·s at 20°C

Stability and Reactivity

Chemical Stability: Stable under normal storage, no dangerous polymerization
Conditions to Avoid: Strong heating, open flames, sources of ignition, direct sunlight
Incompatible Materials: Concentrated acids, strong oxidizers, strong bases
Hazardous Decomposition: Burning releases carbon monoxide, carbon dioxide, small quantities of acetic acid fumes
Other Reactions: Slowly hydrolyzes to acetic acid and propylene glycol in presence of water and acids

Toxicological Information

Acute Toxicity: Low oral toxicity (estimated LD50 rat >2000 mg/kg); unlikely to be highly toxic by skin
Skin Corrosion/Irritation: May produce mild irritation with prolonged contact
Serious Eye Damage: Irritating, can cause redness, tearing, stinging
Respiratory Sensitization: Vapors may irritate the respiratory tract at high concentrations
Chronic Effects: No known carcinogenicity, reproductive toxicity, or organ damage with normal exposure
Other Data: No long-term animal studies available; similar glycol esters generally show low toxicity

Ecological Information

Aquatic Toxicity: Low acute toxicity to fish and aquatic invertebrates (EC50/LC50 >100 mg/L); breaks down in water over time
Persistence: Degrades in environment via hydrolysis and biodegradation
Bioaccumulation: Unlikely to bioaccumulate, low log Kow
Mobility: Moderate mobility, will move through soil with water
Other Environmental Risks: Large spills may damage aquatic and terrestrial habitats

Disposal Considerations

Waste Treatment Methods: Burn in a chemical incinerator with afterburner and scrubber, landfill where allowed
Contaminated Packaging: Rinse containers, offer for recycling or disposal in compliance with local rules
Legal Requirements: Dispose of as hazardous chemical waste if contaminated or in large volumes
Precautions: Avoid release to the environment, keep away from drains and surface water

Transport Information

UN Number: Not regulated under UN Recommendations
Proper Shipping Name: Propylene Glycol Diacetate
Hazard Class: Not classified as dangerous goods by IATA, IMDG, or US DOT
Packing Group: Not applicable
Environmental Hazards: Not marine pollutant
Special Precautions: Ensure containers are sealed and upright during transport, prevent leaking

Regulatory Information

TSCA: Listed on US TSCA inventory
REACH: Registered under EU REACH regulation
OSHA HazCom: Classified as hazardous, subject to labeling requirements
WHMIS (Canada): D2B: Skin/Eye Irritant
SARA Title III: Not listed as a reportable substance
Other Information: No special restrictions in most jurisdictions, always check relevant regional regulations