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Material Safety Data Sheet: Ethylene Glycol Methyl Ether Acetate

Identification

Product Name: Ethylene Glycol Methyl Ether Acetate
Chemical Formula: C5H10O3
Synonyms: 2-Methoxyethyl acetate, EGMEA
CAS Number: 110-49-6
Recommended Use: Solvent in paints, coatings, inks, and cleaners
Manufacturer Information: [Manufacturer name, address, contact number]
Emergency Telephone: [Emergency contact number]

Hazard Identification

Classification: Flammable Liquid (Category 3), Acute Toxicity (Oral, Category 4), Eye Irritation (Category 2)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor, harmful if swallowed, causes serious eye irritation
Pictograms: Flame, Exclamation Mark
Precautionary Statements: Keep away from heat and open flames, avoid breathing vapors, wash thoroughly after handling, wear protective gloves and eye protection, do not eat, drink or smoke when using this product

Composition / Information on Ingredients

Chemical Name: Ethylene Glycol Methyl Ether Acetate
Concentration: 99%+
Impurities: Trace amounts of ethylene glycol methyl ether (EGME), water, and stabilizers
Other Ingredients: None above established disclosure limits

First Aid Measures

Eye Contact: Rinse eyes immediately with plenty of water for at least 15 minutes, seek medical attention right away
Skin Contact: Remove contaminated clothing, wash skin gently with soap and water
Inhalation: Move to fresh air, allow victim to rest, consult a doctor if symptoms persist
Ingestion: Do not induce vomiting, rinse mouth thoroughly with water, seek medical advice promptly
Most Important Symptoms: May cause respiratory tract and eye irritation, headache, drowsiness, or nausea if overexposed

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, foam, or water fog
Unsuitable Media: Direct water stream can spread the liquid
Fire Hazards: Vapors can form explosive mixtures with air, highly flammable, hazardous combustion products include carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective gear
Special Procedures: Cool exposed containers with water spray, avoid inhalation of smoke or fumes, evacuate area if large volume is burning

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate space, eliminate ignition sources, use personal protective equipment
Environmental Precautions: Prevent run-off into drains, waterways or soil
Clean-Up Methods: Contain spill with inert material like sand or vermiculite, collect in sealed chemical waste container, wash spill site after material pickup, dispose in accordance with local regulations

Handling and Storage

Handling: Use in well-ventilated areas, avoid breathing vapor or mist, keep away from sparks and open flames, use spark-proof tools and explosion-proof equipment, wash hands thoroughly after use
Storage: Store tightly closed in a cool, dry, well-ventilated place, keep away from heat, smoking, ignition sources and incompatible materials such as strong acids, alkalis, oxidizers, store in approved flammable liquid containers, keep containers upright and labeled
Incompatible Materials: Strong acids, strong bases, oxidizing agents

Exposure Controls and Personal Protection

Occupational Exposure Limits: OSHA PEL: 25 ppm (skin), ACGIH TLV: 25 ppm TWA (skin)
Engineering Controls: Use mechanical exhaust or local ventilation to keep vapor concentrations below permissible limits
Personal Protective Equipment (PPE): Chemical splash goggles, flame-resistant gloves, impervious clothing, use approved respirator if ventilation is inadequate
Hygiene Measures: Provide eyewash stations and safety showers in work area, remove contaminated clothing immediately, wash hands before eating, drinking, or smoking

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Sweet, ether-like
Boiling Point: 145°C (293°F)
Melting Point: -68°C (-90°F)
Flash Point: 42°C (108°F) (closed cup)
Vapor Pressure: 3.1 mmHg at 20°C
Density: 0.97 g/cm³ at 20°C
Solubility: Miscible with water
Evaporation Rate: 0.38 (butyl acetate=1)
Viscosity: 1.52 mPa.s at 20°C
Auto-Ignition Temperature: 315°C (599 °F)
Partition Coefficient (n-octanol/water): log Kow = -0.25
pH: Not applicable
Upper/Lower Flammability Limits: 1.3% - 13.1% (v/v in air)

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: No hazardous reactions under normal processing
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, formaldehyde (under fire conditions)
Conditions to Avoid: Heat, flames, sparks, incompatibles such as oxidizers and acids, receipts of static electricity
Polymerization: Not expected to occur

Toxicological Information

Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity (Oral): LD50 (rat): 1,600 mg/kg
Acute Toxicity (Dermal): LD50 (rabbit): 5,400 mg/kg
Inhalation Toxicity: LC50 (rat): > 20,000 mg/m³ (4-hour exposure)
Irritation: Causes eye and respiratory tract irritation, mild skin irritation
Chronic Effects: Repeated exposure may cause kidney, liver, or blood disorders, possible reproductive hazard
Carcinogenicity: Not listed by IARC, NTP, OSHA as carcinogen
Other Effects: May affect central nervous system if overexposed, potential teratogen, possible fertility harm

Ecological Information

Ecotoxicity: LC50 (Fish, 96 hr): 53 mg/L (Rainbow trout)
Persistence and Degradability: Biodegradable, breaks down in environment over days to weeks
Bioaccumulation: Low potential for bioaccumulation (log Kow -0.25)
Mobility in Soil: High mobility, soluble in water, can leach to groundwater
Other Adverse Effects: Toxic to aquatic organisms at high concentrations, avoid direct discharge to water bodies

Disposal Considerations

Waste Disposal Methods: Collect waste in compliant containers, follow local, state and federal regulations, send for incineration or chemical treatment at approved facility
Container Disposal: Rinse, destroy, and dispose empty containers as hazardous waste, do not reuse packaging for food or drink
Special Precautions: Avoid dumping in drains, watercourses, or soil, inform environmental authorities if large quantities enter environment

Transport Information

UN Number: UN 1171
Proper Shipping Name: Ethylene Glycol Methyl Ether Acetate
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Hazard Labels: Flammable liquid
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Keep containers upright and sealed during transit, follow transport codes for flammable liquids, restrict exposure to sources of fire and sparks during shipment

Regulatory Information

U.S. OSHA: Classified hazardous under OSHA Hazard Communication Standard
TSCA: Listed in Toxic Substances Control Act Inventory
SARA Section 313: Subject to reporting under SARA Title III
California Prop 65: Listed as reproductive hazard
REACH (EU): Listed, subject to restrictions and authorization
Other Regulations: Subject to workplace exposure limits, Amsterdam Protocol concerns, chemical and flammability storage regulations in most jurisdictions