Product Name: Ethylene Glycol Diethyl Ether
Synonyms: 1,2-Diethoxyethane; Diethyl cellosolve
CAS Number: 112-36-7
Recommended Use: High-boiling solvent in laboratory and industry, chemical intermediate
Supplier: List supplier’s address and contact information
Emergency Contact: Local poison control center or emergency number given by supplier
GHS Classification: Flammable liquid (category 3), Acute toxicity (oral, category 4), Eye irritation (category 2A), Specific target organ toxicity – single exposure (category 3)
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, May cause respiratory irritation, Harmful if swallowed, Flammable liquid and vapor
Precautionary Statements: Avoid breathing vapors or mists, Wash thoroughly after handling, Wear protective gloves/eye protection, Keep away from heat/sparks/open flames/hot surfaces, Use only non-sparking tools, Do not eat, drink or smoke during use
Chemical Name: Ethylene Glycol Diethyl Ether
CAS Number: 112-36-7
Concentration: 99% or above
Impurities that contribute to hazard: Trace materials from manufacturing or transport, such as other glycol ethers in very small amounts, should be checked in the chemical supplier’s report
Inhalation: Remove victim to fresh air, keep at rest, monitor for breathing difficulty, seek medical attention if symptoms persist.
Skin Contact: Wash skin thoroughly with soap and water, remove contaminated clothing and shoes, medical advice needed if irritation develops or persists.
Eye Contact: Rinse eyes with plenty of water for at least 15 minutes, lift eyelids occasionally, get medical help if irritation continues.
Ingestion: Rinse mouth with water, do not induce vomiting unless told by medical professional, give small amounts of water if conscious, get immediate medical attention.
Suitable Extinguishing Media: Dry chemical powder, foam, carbon dioxide, regular alcohol-resistant foam. Water spray for larger fires.
Unsuitable Extinguishing Media: Direct water jet may spread fire.
Specific Hazards: Vapors form explosive mixtures with air, dense vapors may travel along the ground and flash back. Thermal decomposition yields carbon oxides and possibly toxic fumes.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective gear, avoid entering confined spaces without protection.
Special Precautions: Keep all unnecessary personnel away, cool containers with water spray from a safe distance if exposed to fire, prevent water runoff from contaminating waterways.
Personal Precautions: Evacuate non-essential personnel, ventilate area, keep away from ignition sources, use personal protective equipment including suitable gloves, chemical splash goggles, flame-resistant clothing.
Environmental Precautions: Prevent entry into drains, groundwater, or waterways. Inform relevant authorities if contamination occurs.
Cleanup Methods: Absorb spill with inert material like sand or vermiculite, collect and place in properly labeled containers for disposal, wash spill area after cleanup, use spark-proof tools and explosion-proof equipment, ventilate area until vapors clear.
Handling: Handle in a chemical fume hood or well-ventilated area, ground containers to prevent static discharge, avoid inhaling vapors, avoid contact with skin and eyes, keep containers tightly closed when not in use.
Storage: Store in cool, dry, well-ventilated place away from sources of heat, open flames, and incompatible materials (like oxidizing agents, acids), store in original container with proper labeling, segregate from foods and animal feeds, check regularly for leaks or damage.
Occupational Exposure Limits: No specific regulatory limit, but minimize exposure as much as possible, consult local guidance.
Engineering Controls: Use with proper ventilation, fume hoods for laboratory settings, explosion-proof ventilation systems in industrial areas.
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene recommended), safety goggles, face shield, flame-resistant laboratory coat, impervious apron, do not wear contact lenses when handling.
Respiratory Protection: Short-term exposure or spill: Use an approved air-purifying respirator or self-contained breathing apparatus. For large-scale or industrial operations, comprehensive respiratory protection plan needed.
Appearance: Clear, colorless liquid
Odor: Slight, ether-like
Odor Threshold: Not determined
pH: Not applicable (neutral liquid)
Melting Point: -100°C
Boiling Point: 162-164°C
Flash Point: 54°C (closed cup)
Evaporation Rate: Moderate (data not precise)
Flammability: Flammable
Vapor Pressure: 3.7 mm Hg at 25°C
Vapor Density: 5.18 (air = 1)
Relative Density: 0.867 at 20°C
Solubility: Miscible with most organic solvents, slightly soluble in water
Partition Coefficient: log Kow 0.96
Auto-ignition Temperature: 235°C
Decomposition Temperature: Data not established
Viscosity: Low (liquid, flows easily)
Chemical Stability: Stable under recommended storage and handling conditions.
Possibility of Hazardous Reactions: May react with strong oxidizers, acids, alkalis, risk of explosive peroxides with prolonged air exposure.
Hazardous Decomposition Products: Forms carbon monoxide, carbon dioxide, irritating and toxic fumes in fire.
Conditions to Avoid: Open flames, hot surfaces, strong sunlight, static electricity, and direct exposure to air over prolonged periods.
Incompatible Materials: Oxidizing agents, acids, many alkali metals.
Acute Toxicity: Oral LD50 (rat): approx. 1560 mg/kg, Inhalation/dermal data not fully reported but assumed hazardous.
Skin Corrosion/Irritation: Can cause moderate skin irritation after contact.
Eye Damage/Irritation: Cause significant eye irritation, water flushing needed on contact.
Respiratory Sensitization: May cause respiratory tract irritation from inhalation.
Long-term Effects: Repeated/prolonged exposure may cause effects on central nervous system, liver, or kidneys.
Mutagenicity/Carcinogenicity: No strong evidence for mutagenic or carcinogenic effect from available studies, but related glycol ethers have raised health concerns in similar settings.
Ecotoxicity: Harmful to aquatic life with long lasting effects; aquatic organisms can show symptoms from low concentrations.
Persistence and Degradability: Biodegradable in soil and water, but chemical breakdown depends on specific local conditions and may vary.
Bioaccumulative Potential: Low to moderate, log Kow indicates some risk of bioaccumulation in fatty tissues.
Mobility in Soil: Liquid is expected to have high mobility in soil and water owing to low adsorption to solids.
Other Adverse Effects: Spills can pose an oxygen demand hazard in water bodies and stress aquatic environments, recommends measures to keep waste out of waterways.
Waste Treatment Methods: Incinerate controlled by approved waste disposal contractor, do not pour down drains.
Contaminated Packaging: Dispose of as hazardous waste, check local landfill regulations, labels must show chemical composition and regulatory codes.
Precautions: Keep containers tightly sealed, keep chemical until proper waste handling arrives, never mix with household waste, minimize waste as much as possible during use.
UN Number: UN 1993
Proper Shipping Name: Flammable liquid, n.o.s. (contains Ethylene Glycol Diethyl Ether)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Special Precautions for Transport: Ship upright, vent periodically if required by destination climate, keep away from oxidizing agents in transport, transport only in approved containers and vehicles, clearly mark containers with GHS warning symbols and hazard labels, comply with all local and international transport laws.
Safety/Health/Environmental Regulations: Check if listed by OSHA, TSCA, ACGIH, and other local, federal, and international chemical control lists, restrictions vary by country, must follow workplace and transportation safety rules.
Labeling: Product labeling must carry GHS categories, pictograms for flammable and irritant hazards, recommended PPE, storage and handling warnings.
SARA Title III (USA): Not a specifically regulated extremely hazardous substance, but may contribute to overall reportable quantity in mixtures.
REACH (EU): May be subject to registration or further restrictions if marketed or handled in Europe; user responsible for maintaining up-to-date information from suppliers.
Other Information: Regularly update training on chemical safety procedures and availability of MSDS in workplaces, emergency equipment maintenance, and readiness for cleanups, spills, and exposures.
