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Material Safety Data Sheet for Ethylene Glycol Di Methyl Ether

Identification

Product Name: Ethylene Glycol Di Methyl Ether
Synonyms: 1,2-Dimethoxyethane, Monoglyme
CAS Number: 110-71-4
Recommended Use: Solvent in polymer chemistry, lithium battery electrolyte, chemical synthesis
Supplier: Chemical manufacturing companies and laboratory supply vendors
Contact Information: Listed on original supplier documentation; backup emergency line often available on official website
Emergency Phone Number: Reachable through Chemtrec or supplier’s hotline for immediate support in the event of a spill, exposure, or fire

Hazard Identification

Classification: Flammable liquid (Category 2), Eye irritant (Category 2A), Reproductive toxin (Category 2)
Label Elements: GHS symbol for flammability, exclamation mark for irritant, health hazard for toxicity
Hazard Statements: Liquid quickly catches fire, vapors easily ignite, causes eye and skin irritation, inhalation or extended contact may damage fertility or the fetus
Precautionary Statements: Avoid open flames and sparks, ground containers, use only outdoors or with good ventilation, wear protective gear, keep away from children, don’t eat or drink while handling
Potential Health Effects: Shortness of breath, headaches, dizziness on inhalation, nausea, vomiting, dermatitis from skin contact
Environmental Impact: Toxic to aquatic life and possibly persistent in groundwater if not adequately treated

Composition / Information on Ingredients

Chemical Name: 1,2-Dimethoxyethane
Concentration: 99-100% by weight
Molecular Formula: C4H10O2
Molecular Weight: 90.12 g/mol
Impurities: May contain small amounts of methanol or glycol ethers as by-products, specifics depend on supplier and grade

First Aid Measures

Inhalation: Move person to fresh air immediately, offer artificial respiration if breathing has stopped, keep airways clear
Eye Contact: Rinse eyes with water for at least 15 minutes, separate eyelids with fingertips, remove contact lenses if present and easy
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, don’t reuse clothing until laundered
Ingestion: Do not induce vomiting, rinse mouth with plenty of water, seek medical help quickly, show medical staff the container label
Most Important Symptoms: Irritation to skin, eyes, respiratory tract, delayed symptoms might involve nausea, damage to central nervous system

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, foam or carbon dioxide, avoid direct water jet
Specific Hazards: Fire produces toxic fumes like carbon monoxide and carbon dioxide, vapors form explosive mixtures with air, runoff may pollute waterways
Advice for Firefighters: Wear self-contained breathing apparatus and protective clothing, keep upwind, cool exposed containers with water spray, evacuate area as needed
Personal protection: Protective gloves, boots, fire-resistant clothing, goggles or face shield

Accidental Release Measures

Personal Precautions: Isolate area, ventilate, wear chemical goggles, solvent-resistant gloves, and protective clothing
Environmental Precautions: Prevent spillage into sewers or waterways, notify environmental authorities if contamination occurs
Methods for Clean-Up: Absorb spill with inert material like sand or vermiculite, place waste in sealed container for disposal, decontaminate area with water and detergent
Procedures: Avoid producing vapors, keep ignition sources away, coordinate with local emergency response if large amount spilled

Handling and Storage

Handling: Only pour or transfer in well-ventilated places, ground all equipment, keep away from heat, sparks, static, avoid splashing, don’t breathe vapors, wash hands thoroughly after use
Storage: Store in tightly closed containers in cool, dry place, away from strong oxidants and acids, clearly label containers, segregate from food, beverages and feed
Special Notes: Regularly inspect storage area for leaks, maintain proper ventilation, use explosion-proof electrical fixtures

Exposure Controls and Personal Protection

Exposure Limits: OSHA, NIOSH, or ACGIH do not publish official limits, but workplace air levels should stay low
Engineering Controls: Use chemical fume hoods, exhaust fans, spark-proof tools
Personal Protective Equipment: Nitrile or neoprene gloves, full goggles, flame-retardant lab coats, boots, avoid contact lenses
Respiratory Protection: NIOSH-approved organic vapor mask for short or low exposure, full respirator for heavy use
Hygiene Measures: Wash hands and face after handling, shower after long exposure, keep contaminated clothing separate

Physical and Chemical Properties

Appearance: Clear, colorless liquid with faint ether-like odor
Boiling Point: 84-86°C (183-187°F)
Melting Point: -58°C (-72°F)
Flash Point: -2°C (28°F)
Autoignition Temperature: 190°C (374°F)
Vapor Pressure: 82 mm Hg at 20°C
Solubility: Miscible with water, alcohol, ethers, many organic solvents
Density: 0.866 g/cm³ at 20°C
pH: Not applicable
Odor Threshold: Data not fully established, use caution
Viscosity: Low, comparable to water

Stability and Reactivity

Chemical Stability: Stays stable under recommended storage, decomposition possible if heated, exposed to flame, or allowed to contact strong oxidizers
Conditions to Avoid: Sparks, open flames, temperatures above flash point, static charge build-up
Incompatible Materials: Acids, alkali metals, strong oxidizers like peroxides or nitrates, will violently react
Hazardous Decomposition: Burns to form carbon monoxide, carbon dioxide, possibly formaldehyde
Polymerization: No known dangerous polymerization under standard laboratory or industrial handling

Toxicological Information

Routes of Exposure: Inhalation, skin or eye contact, ingestion
Acute Effects: Irritation, headache, dizziness, nausea, central nervous system depression
Chronic Effects: Possible kidney, liver, reproductive system injury with frequent overexposure
LD50 Oral (Rat): Approx 3300 mg/kg
Skin Corrosion/Irritation: Causes irritation on contact, possible delayed dermatitis
Eye Irritation: Causes redness, tearing, burning sensation
Carcinogenicity: Not classified as carcinogen by OSHA, IARC, NTP
Other Effects: May cause adverse effects to human embryo or fetus, avoid for pregnant workers

Ecological Information

Toxicity: Hazardous to aquatic life in large amounts, can negatively impact algae, daphnia, and fish
Persistence and Degradability: Biodegradable in soil and water in moderate time, but persistent in cases of heavy contamination
Bioaccumulative Potential: Not highly bioaccumulative, but repeated exposure should be avoided
Mobility in Soil: Moves easily through soil into groundwater in liquid form, danger of spreading in contaminated run-off
Other Info: Avoid large-scale release to environment, hazardous in municipal wastewater unless professional treatment used

Disposal Considerations

Disposal Methods: Burn in approved chemical incinerator equipped with afterburner and scrubber, follow local disposal regulations
Contaminated Packaging: Triple rinse or steam clean before recycling, treat as hazardous waste
Local Regulations: Consult regional environmental authority, may prohibit sewer or landfill disposal
User Responsibility: Handle unused product and any leftover mixture as harmful chemical waste, consider using professional chemicals contractor

Transport Information

UN Number: 1165
UN Proper Shipping Name: Dimethoxyethane
Hazard Class: 3 (flammable liquid)
Packing Group: II
Environmental Hazards: Not classified as marine pollutant under IMO
Transport Methods: By rail, road, sea, or air under hazardous materials declaration, clear hazard labeling and secure packaging required
Special Precautions: Emergency card required with shipment, notify receiving warehouse to prepare for flammable liquid

Regulatory Information

OSHA Status: Considered hazardous under OSHA Hazard Communication Standard
TSCA Inventory: Listed
SARA Title III: Section 313 not listed, check local amendments
WHMIS Classification (Canada): B2 (combustible liquid), D2A (very toxic), D2B (toxic)
Other Regulations: Handle in accordance with all national, regional, and local laws
Labeling Requirements: Maintain GHS label, pictograms, hazard and precaution statements on all containers
Workplace Controls: Safety procedures required under state, provincial, and federal chemical safety acts