Product Name: Butyl Glycolate
Chemical Formula: C6H12O3
Synonyms: Butyl 2-hydroxyacetate, Butoxyacetic acid butyl ester
CAS Number: 7397-62-8
Recommended Use: Intermediate for chemical synthesis, industrial applications, solvent use
Supplier Contact: Relevant contact details including company name, address, phone number, and emergency contact number should always be on hand for safety reference.
Classification: Eye irritation (Category 2), Skin irritation (Category 2), Specific Target Organ Toxicity – Single Exposure (Category 3)
Label Elements: Pictogram (GHS07: Exclamation mark)
Signal Word: Warning
Hazard Statements: Causes skin and serious eye irritation, may cause respiratory tract irritation
Precautionary Statements: Avoid breathing vapors or mist, wash exposed skin thoroughly, use only in well-ventilated areas, wear protective gloves and eye protection.
Chemical: Butyl Glycolate
Concentration: More than 99% by weight
CAS Number: 7397-62-8
Impurities: Trace amounts of water, glycolic acid or related esters depending on production source.
Inhalation: Remove to fresh air, keep at rest in a position comfortable for breathing, seek medical advice if feeling unwell
Skin Contact: Remove contaminated clothing, flush area with plenty of water for at least 15 minutes, seek medical attention for persistent irritation
Eye Contact: Rinse with lots of water for several minutes, remove contact lenses if present and easy to do, seek prompt medical help for any persistent discomfort
Ingestion: Rinse mouth thoroughly, do not induce vomiting, call a poison center or doctor, never give anything by mouth to an unconscious person.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide
Specific Hazards: Combustible liquid, vapors may form explosive mixture with air, emits toxic fumes under fire conditions including carbon oxides
Protective Equipment: Firefighters need to wear full protective gear, self-contained breathing apparatus should be used in case of fire
Special Precautions: Cool exposed containers with water spray to prevent explosion or re-ignition, keep run-off water out of sewers and drains.
Personal Precautions: Evacuate unnecessary personnel, ensure adequate ventilation, use personal protective equipment as recommended
Environmental Precautions: Prevent leakage or spillage from entering drains, surface and ground water, soil
Methods for Cleaning Up: Stop leak if possible without risk, absorb spillage with inert material such as sand or vermiculite, collect in appropriate containers for disposal, ventilate area thoroughly after clean-up.
Handling: Avoid inhalation and contact with skin and eyes, use only in well-ventilated areas, wash thoroughly after handling, keep work area clean and clear of unnecessary materials
Storage: Store in tightly closed, properly labeled containers, keep in a cool, dry, well-ventilated area away from sources of ignition and incompatible materials like strong acids and bases, store away from direct sunlight and heat sources. Store at temperatures under 25°C to maintain stability.
Engineering Controls: Ensure adequate local exhaust ventilation, use enclosed systems or process isolation where possible
Eye Protection: Safety goggles or face shield suitable for organic solvents
Skin Protection: Chemical resistant gloves (such as nitrile or neoprene), long-sleeved clothing, laboratory coat if working in a lab
Respiratory Protection: Approved organic vapor respirator if ventilation insufficient or exposure limits are exceeded
Hygiene Measures: Wash hands and forearms thoroughly after handling, remove contaminated clothing and wash before reuse.
Appearance: Colorless to pale yellow liquid
Odor: Mild, ester-like
pH: Not applicable in pure state
Boiling Point: 190–193°C
Melting Point: -70°C
Flash Point: 82°C (closed cup)
Vapor Pressure: 0.25 mm Hg at 20°C
Density: 1.03 g/cm³ at 20°C
Solubility: Moderately soluble in water, miscible with most organic solvents
Viscosity: 4.6 mPa·s at 25°C
Partition Coefficient (log Pow): 0.8
Auto-ignition Temperature: 290°C.
Chemical Stability: Stable under recommended conditions for handling and storage
Possible Reactions: Reacts with strong oxidizing agents, strong acids and bases
Conditions to Avoid: Excessive heat, flames, direct sunlight, contact with incompatible substances
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide formed under fire or strong thermal decomposition.
Acute Toxicity: Low acute oral and dermal toxicity, LD50 (oral/rat): ~2500 mg/kg
Skin Contact: Causes moderate irritation, may cause redness and dryness
Eye Contact: Causes severe irritation, may cause watering and redness
Inhalation: Breathing mist or vapor may irritate respiratory tract, cough or sore throat sometimes observed
Long-term Exposure: Repeated or prolonged exposure may cause dermatitis, chronic respiratory irritation
Mutagenicity/Carcinogenicity: No reported carcinogenic or mutagenic effects based on available studies.
Aquatic Toxicity: Low to moderate toxicity for aquatic organisms, LC50 (fish, 96hr): 100–200 mg/L
Mobility: Can migrate in soil and enter groundwater under worst-case spillage
Persistence and Degradability: Readily biodegradable in the environment, breakdown products have low bioaccumulation potential
Bioaccumulation: Not expected to accumulate in biological systems
Other Ecological Hazards: At high concentrations, runoff may affect aquatic life by lowering available oxygen in water.
Product Disposal: Dispose of as hazardous waste in accordance with local regulations, incineration recommended if available, avoid direct release into environment
Contaminated Packaging: Rinse empty containers before recycling or disposal, puncture or crush to prevent reuse, follow all relevant local, state, and federal guidelines
Additional Guidance: Consult with licensed waste disposal contractor; segregation from incompatible waste materials is fundamental.
UN Number: UN 1993
Proper Shipping Name: Flammable liquid, n.o.s. (contains Butyl Glycolate)
Transport Hazard Class: 3 (Flammable Liquids)
Packing Group: III
Labels: Flammable Liquid symbol required on packages
Environmental Hazards: Not classified as marine pollutant
Special Precautions After Transport: Keep containers tightly secured and upright, ensure adequate labeling during all segments of transport chain.
EU Regulations: Registered under REACH, subject to workplace exposure limits for solvents
US Regulations: TSCA-listed, not classified as a regulated hazardous air pollutant by the Clean Air Act, SARA Title III Section 313 not applicable
Other International: Listed in relevant inventories in Australia, Canada, Japan, and Korea
Workplace Controls: Occupational safety protections required under OSHA, adequate information and training must be provided to personnel
Labelling Requirements: Conforms to GHS labeling, hazard statements, and precautionary statements must appear on containers and storage locations.
