Product Name: 2-Methoxy-1-Propanol Acetate
Synonyms: Propylene glycol methyl ether acetate, PGMEA
CAS Number: 70657-70-4
Recommended Use: Solvent used in coatings, inks, cleaners, adhesives
Supplier: Chemical manufacturers or distributors, addresses vary by supplier
Emergency Phone: Provided on product label or supplier documentation
GHS Classification: Flammable Liquid Category 3, Eye Irritation Category 2A, Specific Target Organ Toxicity (Single Exposure) Category 3 (narcotic effects)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor, Causes serious eye irritation, May cause drowsiness or dizziness
Pictograms: Flame, Exclamation mark
Precautionary Statements: Keep away from heat/sparks/open flames/hot surfaces, Wear protective gloves and eye protection, Use only outdoors or in well-ventilated area, Avoid breathing vapors
Physical Hazards: Releases vapors that can form explosive mixtures with air, May accumulate static charge during transfer
Chemical Name: 2-Methoxy-1-Propanol Acetate
Synonyms: Propylene glycol methyl ether acetate, PGMEA
CAS Number: 70657-70-4
Concentration: >99% (varies by supplier, check label)
Impurities: Trace impurities possible depending on supplier, detailed composition available upon request
Inhalation: Move to fresh air, keep at rest in position comfortable for breathing. If symptoms persist, get medical attention
Skin Contact: Remove contaminated clothing, wash exposed skin with soap and water. Seek medical attention for persistent irritation
Eye Contact: Rinse with water for at least 15 minutes, remove contact lenses if present and easy to do. Get medical help for irritation or redness
Ingestion: Rinse mouth, do NOT induce vomiting. Seek medical attention for any discomfort, show SDS to medical personnel
General Notes: Immediate medical attention recommended in case of persistent or severe symptoms, care for affected persons until help arrives
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray may be used for surrounding fire but not direct streams
Unsuitable Extinguishing Media: Direct water jets (may spread fire)
Specific Hazards: Vapors may travel to ignition sources, hazardous combustion products include carbon monoxide, carbon dioxide, irritating fumes
Protective Equipment: Full protective clothing, self-contained breathing apparatus for advanced response
Fire Fighting Instructions: Cool tanks and containers with water spray, avoid inhaling combustion products, evacuate area as necessary
Personal Protection: Ventilate area, avoid breathing vapors, wear protective gloves and goggles
Environmental Precautions: Prevent entry to watercourses and drains, contain spill with non-combustible absorbent material like sand or earth
Methods for Containment: Stop leak if without risk, dike and soak up with inert absorbent. Collect in labeled containers
Cleanup Procedures: Use non-sparking tools to collect residue, dispose according to local regulations, ventilate area after cleanup
Safe Handling: Use away from sources of ignition, ground equipment, avoid inhaling vapors, avoid eye and skin contact, keep containers closed when not in use
Precautions: Work in well ventilated space, use spark-proof tools, avoid eating or drinking around product
Storage Conditions: Store in tightly sealed original container, in cool and well-ventilated area, away from sparks, heat, open flames, and oxidizing agents
Incompatible Materials: Strong acids, alkalis, oxidizers can cause dangerous reactions or degradation
Exposure Limits: OSHA/ACGIH TLV-TWA: 50 ppm (270 mg/m3) where established
Engineering Controls: Ventilation systems to lower vapor concentration, especially in confined spaces
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), splash goggles, long-sleeved clothing, in higher exposure scenarios use organic vapor respirators
Work Practices: Regular cleaning of skin, safety showers, and eyewash stations close to working area
Appearance: Clear, colorless liquid
Odor: Mild ether-like odor
Odor Threshold: Not readily available
pH: Not applicable
Melting/Freezing Point: −64°C
Boiling Point: 146°C
Flash Point: 47°C (closed cup)
Evaporation Rate: Moderate, slower than diethyl ether
Flammability: Flammable liquid
Upper/Lower Explosion Limits: 1.5–13.1% by volume in air
Vapor Pressure: 3.7 mmHg @ 20°C
Relative Density: 0.956 g/cm³ @ 20°C
Solubility: Miscible with water and most organic solvents
Partition Coefficient (n-octanol/water): 0.36 (estimated)
Autoignition Temperature: 340°C
Decomposition Temperature: Above 200°C
Viscosity: 1.1 mPa·s @ 25°C
Chemical Stability: Stable under ordinary conditions of use and storage
Conditions to Avoid: Heat, sparks, flame, strong oxidizers
Incompatible Materials: Strong acids, bases, oxidizing chemicals, some plastics
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possible toxic fumes if burned or decomposed in fire
Hazardous Reactions: May react with peroxides, avoid mixing with strong oxidizers
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Inhalation can cause dizziness, drowsiness; LD50 oral (rat): approximately 5,000 mg/kg; LD50 dermal (rabbit): approximately 2,000 mg/kg
Skin and Eye Irritation: Moderate irritation to skin and serious eye irritation
Respiratory Effects: High vapor concentrations can cause dizziness, headache, and central nervous system depression
Chronic Effects: Prolonged or repeated exposure may cause dermatitis
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a carcinogen
Ecotoxicity: Not expected to be highly toxic to aquatic organisms, LC50 (fish, 96hr): >100 mg/L (estimated)
Persistence and Degradability: Readily biodegradable, breaks down in environment within weeks
Bioaccumulation: Low potential (log Kow: 0.36)
Mobility in Soil: High water solubility, likely to migrate in groundwater if released
Other Adverse Effects: Spills can create slicks on water, excessive amounts may affect aquatic life
Waste Disposal: Collect and contain as hazardous waste, contact licensed waste disposal professionals
Container Handling: Triple rinse then offer container for recycling or disposal as chemical waste, puncture and drain before landfill if permitted by regulations
Environmental Precautions: Avoid release to soil, waterways, or sewers, comply with local, regional, and national disposal rules
Incineration: Professional facilities equipped to handle chemical vapors and water-soluble waste products recommended
Cleanup Materials: Dispose absorbents as chemical waste, minimize contamination of non-hazardous waste streams
UN Number: 3272
Proper Shipping Name: Esters, n.o.s. (contains 2-Methoxy-1-Propanol Acetate)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Labels: Flammable liquid
Special Precautions: Use tightly closed containers, keep away from sources of ignition during transport, follow ADR, DOT, IMDG, IATA/ICAO requirements as needed
OSHA: Classified as hazardous based on flammability and health effects, subject to Hazard Communication Standard
SARA Title III: Not listed under Extremely Hazardous Substances, but reportable if released in large quantities
TSCA: Listed
REACH: Registered (European Union)
California Prop 65: Not listed as a carcinogen or reproductive toxin
Canada WHMIS: Flammable liquid, eye irritant
Other Global Regulations: Regulations may vary, review local chemical control laws regarding labeling, transport, handling
