Chemical Name: 2-Ethoxyethanol
Synonyms: Ethylene glycol monoethyl ether, Cellosolve, Ethyl cellosolve
CAS Number: 110-80-5
Product Use: Used as a solvent in paints, coatings, and inks, as well as in chemical synthesis
Supplier Details: Information available from manufacturer or supplier
Emergency Telephone Number: Reference specific supplier for up-to-date contact
Classification: Flammable liquid, acute toxicity (oral and dermal), eye irritation, reproductive toxicity
Signal Word: Danger
Hazard Statements: Harmful if swallowed, inhaled, or absorbed through skin. May cause respiratory tract irritation. May damage fertility or unborn child. Flammable liquid and vapor.
Pictograms: Flame, Health Hazard, Exclamation Mark
Precautionary Statements: Keep away from heat, spark, open flames. Avoid breathing vapors, wear protective gloves and eye protection. Wash exposed skin thoroughly after handling. If exposed or if you feel unwell: seek medical advice.
Potential Health Effects: Exposure can lead to symptoms such as headache, dizziness, nausea, drowsiness. Long-term exposure may affect blood, kidneys, liver, and reproductive system. Can cause eye and skin irritation.
Chemical Name: 2-Ethoxyethanol
CAS Number: 110-80-5
Concentration: Over 99% pure substance; may contain trace impurities from manufacturing
Other Ingredients: Usually not present in significant concentrations. For specific mixtures, consult supplier.
Inhalation: Remove person to fresh air promptly. If breathing becomes difficult, give oxygen and call for medical attention. Move to a quiet area and keep warm.
Skin Contact: Remove contaminated clothing. Rinse skin immediately with plenty of water for 15 minutes. If irritation persists, see a physician.
Eye Contact: Flush eyes thoroughly with water for at least 15 minutes, lifting both upper and lower eyelids occasionally. Seek medical assistance after rinsing.
Ingestion: Rinse mouth with water. Seek immediate medical advice. Do not induce vomiting unless instructed by medical personnel.
Symptoms: Headache, nausea, confusion, drowsiness, irritation of skin and eyes, abdominal pain, unconsciousness in severe cases.
Advice for Medical Staff: Treat symptomatically. Monitor for signs of respiratory distress or metabolic acidosis. Consider consulting poison control or toxicologist.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide for extinguishing fires involving 2-ethoxyethanol.
Unsuitable Media: Avoid using direct water jet as it may spread the fire.
Special Hazards: Vapors form explosive mixtures with air. May release toxic fumes including carbon monoxide, carbon dioxide under combustion.
Protective Equipment for Firefighters: Use full protective clothing including self-contained breathing apparatus. Keep containers cool with water spray.
Advice: Evacuate area, remove ignition sources, monitor for toxic gases. Prevent runoff from fire control entering waterways or sewers.
Personal Precautions: Evacuate unnecessary personnel. Use chemical-resistant gloves, eye protection, and appropriate respirator. Avoid breathing vapors.
Environmental Precautions: Prevent spilled material from entering drains, soil, or watercourses. Report releases to local authorities as required.
Methods for Clean-Up: Contain spillage. Absorb with inert material such as sand or earth, then place in container for disposal. Clean contaminated area thoroughly with water. Wash spills promptly, ventilate area.
Special Procedures: Ventilate closed spaces before entry, supervise clean-up with trained personnel, minimize risk of exposure.
Handling: Work in well-ventilated location, away from heat, sparks, or flames. Use proper protective equipment. Avoid breathing vapor and direct contact with skin or eyes. Do not eat, drink, or smoke during use.
Storage: Store in tightly closed container, in dry, cool, well-ventilated space. Keep separate from oxidizing agents, acids, and strong bases. Store away from direct sunlight and incompatible substances.
Hygiene Practices: Wash hands and face thoroughly after handling. Remove contaminated clothing and wash before re-use.
Engineering Recommendations: Use proper grounding and bonding to prevent static discharge. Maintain equipment in good condition.
Exposure Limits: OSHA PEL: 200 ppm TWA, ACGIH TLV: 5 ppm (skin) TWA
Engineering Controls: Use local exhaust or general room ventilation to keep vapor concentrations below permissible limits. Consider explosion-proof equipment.
Personal Protective Equipment:
Gloves: Chemical-resistant (e.g., nitrile, neoprene).
Eye/Face Protection: Chemical safety goggles.
Respiratory Protection: Approved respirator if ventilation is inadequate or exposure limits are exceeded.
Clothing: Long sleeves, laboratory coat, apron where splashing likely.
Work Practices: Avoid accidental ingestion, inhalation, or skin contact by using controlled environment.
Appearance: Colorless, odorless to mild ether-like smelling liquid
Odor: Mild, sweet, ether-like
Boiling Point: 135°C (275°F)
Melting Point: -70°C (-94°F)
Flash Point: 44°C (111°F) (closed cup)
Autoignition Temperature: 230°C (446°F)
Vapor Pressure: 5 mmHg @ 25°C (77°F)
Specific Gravity: 0.93 @ 20°C (68°F)
Solubility: Miscible in water
Evaporation Rate: Slower than butyl acetate
Viscosity: 1.54 mPa·s at 20°C
Partition coefficient: log Kow = -0.32
Stability: Stable under recommended storage conditions. Reacts with strong oxidizing agents.
Incompatible Materials: Strong oxidizers, acids, alkalis. Possibility of violent reaction.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, potentially irritating and toxic fumes on combustion.
Polymerization: Will not polymerize under normal handling.
Conditions to Avoid: Sources of heat, flame, sparks. Prolonged exposure to air and sunlight.
Routes of Exposure: Inhalation, skin absorption, ingestion.
Acute Toxicity: LD50 Oral (rat): 1,950 mg/kg. LD50 Dermal (rabbit): 3,800 mg/kg.
Chronic Toxicity: Prolonged exposure may impair blood, liver, kidney, and reproductive function.
Carcinogenicity: Not classified by IARC as human carcinogen. Evidence of developmental and reproductive toxicity.
Symptoms of Overexposure: Headache, dizziness, abdominal pain, anemia, blood disorders, nervous system effects.
Sensitization: Not considered a skin sensitizer.
Other Information: Eye and skin irritant; evidence of toxic effects from epidemiological and animal studies.
Environmental Fate: Readily biodegradable under aerobic conditions. No significant bioaccumulation expected.
Aquatic Toxicity: LC50 (Fish, 96 hr): 8,400 mg/L (rainbow trout). EC50 (Daphnia, 48 hr): 3,900 mg/L.
Persistence and Degradability: Rapidly breaks down in soil and water.
Mobility in Soil: High mobility, may leach to groundwater.
Potential Environmental Impact: Spills in bulk may pose risk to aquatic organisms, particularly in confined water bodies.
Other Adverse Effects: Not considered a persistent organic pollutant. No ozone depletion potential.
Waste Disposal Methods: Dispose of through licensed chemical waste contractor. Comply with all local, regional, national, and international regulations.
Contaminated Packaging: Triple rinse empty containers and forward for recycling or disposal as hazardous waste.
Special Precautions: Do not allow spills, cleaning residues, or rinsate to reach sewer or water bodies. Consult local environmental agency.
Regulatory Codes: U.S.: EPA hazardous waste number U154.
UN Number: UN1171
Proper Shipping Name: Ethylene glycol monoethyl ether
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Labels Required: Flammable Liquid
Environmental Hazards: Not listed as a marine pollutant
Special Precautions for User: Avoid sparks or flames during transport. Secure all containers upright.
Transport Regulations: Comply with DOT, ICAO/IATA, IMDG, ADR regulations for safe shipping.
U.S. Regulations: SARA 313 listed, subject to reporting. TSCA inventory. CERCLA reportable quantity: 1000 lbs.
Canada: DSL/NDSL Listed, WHMIS Classification: D1B (Toxic), D2A (Teratogenicity); B2 (Flammable).
European Union: Listed on EINECS. Classification: R10, R60, R61, R20/21/22. Subject to REACH controls.
Australia: AICS listed.
Other International: Check with local country laws and regulations for specific restrictions and reporting requirements.
